When you consider that these are ONLY the deaths the US admit to, and only up to Jul 2016, the actual figure would likely be around 10 times greater during that period, when all coalition air strikes are taken into account or at least 1200 people probably more! Add to that the civilian deaths, as yet unreported in Mosul and according to unconfirmed reports are well over a 1000, then civilian casualties attributed to the US coalition are substantial. If the deaths attributed to coalition forces are in Syria ..... they are war crimes, as Amnesty points out.
U.S. military announces that civilian casualties in Iraq and Syria are more than double previous estimate
The announcement of 64 additional deaths brings the total civilian death toll in U.S. air attacks to 119 since the campaign against the Islamic State began in 2014, Centcom said. The command, responsible for U.S. military operations in the Middle East, is investigating other allegations.
https://www.washingtonpost.com/news/checkpoint/wp/2016/11/09/u-s-military-announces-that-civilian-casualties-in-iraq-and-syria-are-more-than-double-previous-estimate/?utm_term=.f2f298378732
Rights group calls Pentagon’s Syrian civilian casualty probes inadequate, incomplete
Following a detailed study, Amnesty International concluded that a series of attacks from September 2014 to July 2016 killed at least 300 people. Some of the raids by the United States and its allies, the group said, may have violated international humanitarian law.
https://www.washingtonpost.com/news/checkpoint/wp/2016/10/25/rights-group-calls-pentagons-syrian-civilian-casualty-probes-inadequate-incomplete/?tid=a_inl&utm_term=.a1c7fbef0d83