Cyprus-Forum.com

[Captain Pugwash]

THE CYPRIOT GENETIC CHALLENGE
1} Cyprus is a gene pool of Cypriots, whichever side of the green line your on.
2} Cypriots suffer from delusions of xenophilic / xenophobia (Bigotrismic myopia).
In fact, Cypriots are genetically more similar to each other, than either Turks or Greeks! (Thallasaemia - trait, is very common to the Island, but not Turkey or Greece.
3} Therefore, take the 'Genome Challenge', & go under the microscope, into the cells that imprison your DNA, & if it comes up Cypriot - 'pull up the wire'. The others return to their Country of Origin.
Troops go home, everyone's happy.

Hypothesis: The idea itself imparts terror into the hearts of all Cypriots, since it just may be correct.
Thus, Cyprus carries on, as always, that if it is some other bugger's fault.
Why? As the scorpion stung the frog, who he'd convined to carry him across the lake, stinging him, was perillous to them both. As they drowned, the frog asked why?, 'Because it is my nature replied the scorpion'!

[Panicos UK]

THE CYPRIOT GENETIC CHALLENGE
1} Cyprus is a gene pool of Cypriots, whichever side of the green line your on.
2} Cypriots suffer from delusions of xenophilic / xenophobia (Bigotrismic myopia).
In fact, Cypriots are genetically more similar to each other, than either Turks or Greeks! (Thallasaemia - trait, is very common to the Island, but not Turkey or Greece.
3} Therefore, take the 'Genome Challenge', & go under the microscope, into the cells that imprison your DNA, & if it comes up Cypriot - 'pull up the wire'. The others return to their Country of Origin.
Troops go home, everyone's happy.

Many ethnic Greeks converted to Islam when the island was invaded in 1571. We don't know how many thousands of ethnic Greek women were raped and gave birth to mixed Turkish/Greek children. So you're right, Cyprus is a 'gene pool' of Cypriots. This doesn't mean that the Greek Cypriots are NOT Greek. Being 'Greek' doesn't mean we are 'like the mainlanders'. The mainlanders are a certain type of Greek, the Cretans are another type of Greek, the Majority of Cypriots are another type of Greek and the Greeks from Asia Minor/Istanbul area are a different type as well. It's less to do with place of birth or what 'state' you are a citizen in and more to do with language, culture, traditions, religions etc and what you feel you are. Look at the Kurds. They have no official country or state yet they are one people 'the Kurds'. There are Iraqi Kurds and Turkish Kurds, but they identify with the label 'Kurd'.

[GreekIslandGirl]

In fact, Cypriots are genetically more similar to each other, than either Turks or Greeks! (Thallasaemia - trait, is very common to the Island, but not Turkey or Greece.
3} !

Unless you have some substantial, recent data to back this statement, you better give up on your thesis. Thallasaemia is an environmentally selected mutation and the longer Turks stay near the Mediterranean, the more they will independently acquire these mutations. Of which more 'rare' mutations are discovered all the time.

For example:



Hemoglobin. 2001 May;25(2):241-5.
Genetic heterogeneity of beta-thalassemia at Cukurova in southern Turkey.
Cürük MA, Arpaci A, Attila G, Tuli A, Kilinç Y, Aksoy K, Yüreğir GT.
Source
Institute of Molecular Medicine and Genetics, Medical College of Georgia, Augusta 30912, USA.
Abstract
Beta-thalassemia is the most common genetic abnormality causing health problems worldwide. Cukurova, in the southern part of Turkey, being on the Mediterranean, is in the thalassemic belt. Since there is no cure for the disease at present, the frequency of the mutation types of beta-thalassemia must first be identified to aid in clinical follow-up and prenatal diagnosis. Carriers identified during a screening survey and patients referred to our laboratory were studied for this purpose. After routine hematological analysis molecular screening was performed by the amplification refractory mutation system and DNA sequencing. The frequency of the common mutations were: IVS-I-110 (G-->A) 57.3%, IVS-I-1 (G-->A) 8.3%, codon 39 (C-->T) 6.4%, IVS-I-6 (T-->C) 5.7%, frameshift codon 8 (-AA) 5.7%, -30 (T-->A) 4.7%, IVS-II-1 (G-->A) 3.4%, IVS-II-745 (G-->C) 2.8%, and frameshift codon 5 (-CT) 1.1%. Some rare mutations (1%) such as frameshift codon 44 (-C) 0.7%, frameshift codons 74/75 (-C) 0.7%, IVS-1-5 (G-->C) 0.7%, frameshift codons 8/9 (+G) 0.4%, frameshift codons 36/37 (-T) 0.4%, frameshift codons 22/23/24 (-AAGTTGG) 0.4%, IVS-1-130 (G-->C) 0.4%, IVS-1-5 (G-->T) 0.2%, -28 (A-->C) 0.2%, codon 15 (TGG-->TGA) 0.2%, and frameshift codons 82/83 (-G) 0.2%, were detected by sequence analysis. The codon 15 (TGG-->TGA) and frameshift codons 82/83 (-G) mutations were seen in Turkey for the first time.


.....................................................................



Am J Hematol. 2000 Apr;63(4):223-5.
A rare mutation [IVS-I-130 (G-A)] in a Turkish beta-thalassemia major patient.
Tadmouri GO, Bilenoğlu O, Kantarci S, Kayserili H, Perrin P, Başak AN.
Source
Department of Molecular Biology, Boğaziçi University, Bebek, Istanbul, Turkey.
Abstract
Here we describe the identification of the rare beta-thalassemia mutation IVS-I-130 (G-A) for the first time in Turkey. The hematological evaluation of the patient showed classical signs of beta-thalassemia major requiring regular blood transfusions every 30-35 days. DNA analysis was carried out using reverse dot-blot hybridization and restriction endonuclease digestion, as well as genomic sequencing. The patient was found to be heterozygous for the IVS-I-6 (T-C) and IVS-I-130 (G-A) mutations. In order to deduce a possible origin for the IVS-I-130 (G-A) mutation, the sequence polymorphisms in the DNA of the patient and her family were characterized. The method included the analysis of nine polymorphic nucleotides and the hypervariable microsatellite of composite sequence (AT)(x)T(y) 5' to the beta-globin gene by DNA sequencing. The sequence haplotype (HT4) carrying the IVS-I-130 (G-A) mutation is also observed in Algeria. This favors a Northeastern African origin for this allele. The observed results agree well with a recent introduction of this mutation to Turkey from Egypt toward the end of the 19th century.

[Get Real!]

In fact, Cypriots are genetically more similar to each other,

I'm buffled!

I thought they'd be more Pakistani crossed with Cuban...

[CBBB]

It is obvious that Captain Pugwash with the assistance of Master Bates has been examining the genetic make-up of Seaman Staines!

[GreekIslandGirl]

Hellloooooo ... Pugwash! Where are yuoooo???

Have you found some recent data to back up your claims? Because you made me go searching (Science, 2009) and there's some confirmation that you are talking rubbish. For example - Something interesting about the distribution of thalassaemia in Turkey;

The 30, T->A is predominant in Turkey (3.1) and Egypt,Tunisia and Syria... But NOT Greece (0.1) or Cyprus (0) . The CDS-CT is prominent in Turkey (2.3), Syria, Tunisia and UAE, but NOT in Cyprus and Greece. As for CD8 (something) - it's 5.4 in Turkey, high in Morroco, Lebanon, Kuwait - but NOT in Cyprus or Greece!

Overall the Greece profiles are well distributed for a typical Mediterranean climate and Cyprus remains fairly unique (some similarity to Italy, probably due to Sicily and the Mycenaean connection) maybe because of its African proximity and Island nature - as to be expected. All's well in the biological environs and safe from racist determinants

Hate to bring up Hitler, but he is the only one (apart from Turks?) who latches on to qualify their reason for being, as a biological ordination.

[supporttheunderdog]

Hellloooooo ... Pugwash! Where are yuoooo???

Have you found some recent data to back up your claims? Because you made me go searching (Science, 2009) and there's some confirmation that you are talking rubbish. For example - Something interesting about the distribution of thalassaemia in Turkey;

The 30, T->A is predominant in Turkey (3.1) and Egypt,Tunisia and Syria... But NOT Greece (0.1) or Cyprus (0) . The CDS-CT is prominent in Turkey (2.3), Syria, Tunisia and UAE, but NOT in Cyprus and Greece. As for CD8 (something) - it's 5.4 in Turkey, high in Morroco, Lebanon, Kuwait - but NOT in Cyprus or Greece!

Overall the Greece profiles are well distributed for a typical Mediterranean climate and Cyprus remains fairly unique (some similarity to Italy, probably due to Sicily and the Mycenaean connection) maybe because of its African proximity and Island nature - as to be expected. All's well in the biological environs and safe from racist determinants

Hate to bring up Hitler, but he is the only one (apart from Turks?) who latches on to qualify their reason for being, as a biological ordination.

I understood The claim to Greekness is at least in part based on an alleged decent from Greeks

{quote="oracle"]Yes, the predomint genetic influence in Cyprus is Greek and any other influence is minor! [/quote]

[GreekIslandGirl]

Hellloooooo ... Pugwash! Where are yuoooo???

Have you found some recent data to back up your claims? Because you made me go searching (Science, 2009) and there's some confirmation that you are talking rubbish. For example - Something interesting about the distribution of thalassaemia in Turkey;

The 30, T->A is predominant in Turkey (3.1) and Egypt,Tunisia and Syria... But NOT Greece (0.1) or Cyprus (0) . The CDS-CT is prominent in Turkey (2.3), Syria, Tunisia and UAE, but NOT in Cyprus and Greece. As for CD8 (something) - it's 5.4 in Turkey, high in Morroco, Lebanon, Kuwait - but NOT in Cyprus or Greece!

Overall the Greece profiles are well distributed for a typical Mediterranean climate and Cyprus remains fairly unique (some similarity to Italy, probably due to Sicily and the Mycenaean connection) maybe because of its African proximity and Island nature - as to be expected. All's well in the biological environs and safe from racist determinants

Hate to bring up Hitler, but he is the only one (apart from Turks?) who latches on to qualify their reason for being, as a biological ordination.

I understood The claim to Greekness is at least in part based on an alleged decent from Greeks

{quote="oracle"]Yes, the predomint genetic influence in Cyprus is Greek and any other influence is minor!

It is. You have never shown otherwise. The data above demonstrate to the thread theorist some of what is wrong with what he states.

STUD - do you have any idea what 'genetic' means? I did suggest you invest your time, more suitably, in learning some Greek - for a start.

[supporttheunderdog]

blame the cat - i was half way through a reply which was incomplete when the cat walked on the keyboard - you will however get one.

[SKI-preo]

Ladies marry a thalasemmic

Thalassemia can often cause priapism!