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[zan]

lend me your Kidneys!!!

Single Cypriot ancestor responsible for widespread kidney disease
By Darya Alikhani
Published on August 27, 2010
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A GENETIC mutation in the immune system– dating back to a single common ancestor more than three centuries ago -- leads to chronic kidney disease, which seems to exclusively affect people of Cypriot origin, a study has found.
Further analysis, which does not form part of this study suggests that a minimum of about one in every 6,000 Cypriots has the mutation.
“All the families affected so far are of Cypriot origin and the researchers believe this mutation represents a significant proportion of the kidney disease burden in Cyprus and in Cypriot families worldwide,” according to the article, published in the leading medical journal The Lancet.
The article is by Professor Patrick Maxwell, The Rayne Institute, University College London, UK, and colleagues, and is funded by the UK Medical Research Council and The Wellcome Trust.
In the article, the researchers have identified the disease—which they have named CFHR5 nephropathy—in 28 people from five families. All are of Cypriot descent and some are living in the UK.
Symptoms include blood in the urine—sometimes microscopic, sometimes visible—and progressive kidney malfunction.
Existing guidelines state that, if not accompanied by traces of protein, urinary tract abnormalities or impairment to the kidneys, blood in the urine is considered benign.
But the researchers show in this new study that in certain cases it can signal progressive chronic kidney disease.
The researchers, based in the UK, Cyprus, France, and Spain, identified an inherited kidney disorder caused by the mutation in gene CFHR5.
The authors said their genetic analysis suggests the mutation probably dates back 16 generations to a single ancestor.
"High instance of blood in the urine, the wide geographical distribution of ancestry within Cyprus, and the presence of affected individuals in the UK suggests that this disease will account for a substantial proportion of renal disease affecting inhabitants of the island and their descendants worldwide," the authors said.
They predict that this one mutation could be responsible for between 1.0 and 2.0 per cent of all kidney disease cases in Cypriots.
Further analysis that does not form part of this study suggests that a minimum of about one in every 6,000 Cypriots has the mutation.

[DT.]

lend me your Kidneys!!!

Single Cypriot ancestor responsible for widespread kidney disease
By Darya Alikhani
Published on August 27, 2010
+
-
Text size

RELATED CONTENT
Man enters 10km race after third kidney transplant
Turkish Cypriot given kidney transplant in the south after beating by Turkish officer
Singer gears up for charity bike ride
Pub puts in for kidney charity
TOPIC TAGS
Cyprus
Follow the mail on Twitter.
A GENETIC mutation in the immune system– dating back to a single common ancestor more than three centuries ago -- leads to chronic kidney disease, which seems to exclusively affect people of Cypriot origin, a study has found.
Further analysis, which does not form part of this study suggests that a minimum of about one in every 6,000 Cypriots has the mutation.
“All the families affected so far are of Cypriot origin and the researchers believe this mutation represents a significant proportion of the kidney disease burden in Cyprus and in Cypriot families worldwide,” according to the article, published in the leading medical journal The Lancet.
The article is by Professor Patrick Maxwell, The Rayne Institute, University College London, UK, and colleagues, and is funded by the UK Medical Research Council and The Wellcome Trust.
In the article, the researchers have identified the disease—which they have named CFHR5 nephropathy—in 28 people from five families. All are of Cypriot descent and some are living in the UK.
Symptoms include blood in the urine—sometimes microscopic, sometimes visible—and progressive kidney malfunction.
Existing guidelines state that, if not accompanied by traces of protein, urinary tract abnormalities or impairment to the kidneys, blood in the urine is considered benign.
But the researchers show in this new study that in certain cases it can signal progressive chronic kidney disease.
The researchers, based in the UK, Cyprus, France, and Spain, identified an inherited kidney disorder caused by the mutation in gene CFHR5.
The authors said their genetic analysis suggests the mutation probably dates back 16 generations to a single ancestor.
"High instance of blood in the urine, the wide geographical distribution of ancestry within Cyprus, and the presence of affected individuals in the UK suggests that this disease will account for a substantial proportion of renal disease affecting inhabitants of the island and their descendants worldwide," the authors said.
They predict that this one mutation could be responsible for between 1.0 and 2.0 per cent of all kidney disease cases in Cypriots.
Further analysis that does not form part of this study suggests that a minimum of about one in every 6,000 Cypriots has the mutation.

Don't worry, you'll be fine. I am surprised you missed out one of the titles in the related stories. Here it is I made it bigger for your eye sight,

Turkish Cypriot given kidney transplant in the south after beating by Turkish officer

[zan]

lend me your Kidneys!!!

Single Cypriot ancestor responsible for widespread kidney disease
By Darya Alikhani
Published on August 27, 2010
+
-
Text size

RELATED CONTENT
Man enters 10km race after third kidney transplant
Turkish Cypriot given kidney transplant in the south after beating by Turkish officer
Singer gears up for charity bike ride
Pub puts in for kidney charity
TOPIC TAGS
Cyprus
Follow the mail on Twitter.
A GENETIC mutation in the immune system– dating back to a single common ancestor more than three centuries ago -- leads to chronic kidney disease, which seems to exclusively affect people of Cypriot origin, a study has found.
Further analysis, which does not form part of this study suggests that a minimum of about one in every 6,000 Cypriots has the mutation.
“All the families affected so far are of Cypriot origin and the researchers believe this mutation represents a significant proportion of the kidney disease burden in Cyprus and in Cypriot families worldwide,” according to the article, published in the leading medical journal The Lancet.
The article is by Professor Patrick Maxwell, The Rayne Institute, University College London, UK, and colleagues, and is funded by the UK Medical Research Council and The Wellcome Trust.
In the article, the researchers have identified the disease—which they have named CFHR5 nephropathy—in 28 people from five families. All are of Cypriot descent and some are living in the UK.
Symptoms include blood in the urine—sometimes microscopic, sometimes visible—and progressive kidney malfunction.
Existing guidelines state that, if not accompanied by traces of protein, urinary tract abnormalities or impairment to the kidneys, blood in the urine is considered benign.
But the researchers show in this new study that in certain cases it can signal progressive chronic kidney disease.
The researchers, based in the UK, Cyprus, France, and Spain, identified an inherited kidney disorder caused by the mutation in gene CFHR5.
The authors said their genetic analysis suggests the mutation probably dates back 16 generations to a single ancestor.
"High instance of blood in the urine, the wide geographical distribution of ancestry within Cyprus, and the presence of affected individuals in the UK suggests that this disease will account for a substantial proportion of renal disease affecting inhabitants of the island and their descendants worldwide," the authors said.
They predict that this one mutation could be responsible for between 1.0 and 2.0 per cent of all kidney disease cases in Cypriots.
Further analysis that does not form part of this study suggests that a minimum of about one in every 6,000 Cypriots has the mutation.

Don't worry, you'll be fine. I am surprised you missed out one of the titles in the related stories. Here it is I made it bigger for your eye sight,

Turkish Cypriot given kidney transplant in the south after beating by Turkish officer

Hope it wasn't one of those from GRs camp

[Malapapa]

A GENETIC mutation in the immune system– dating back to a single common ancestor more than three centuries ago -- leads to chronic kidney disease, which seems to exclusively affect people of Cypriot origin,

What did I tell you? If your slovenly ancestors had remained "true Cypriots" and hadn't chosen the easy option to "convert" to Islam all those centuries ago during Ottoman rule, Cyprus wouldn't be in the mess she's in now. Granted, we'd still have kidney problems, but at least Turkey would be out of our hair.

[zan]

A GENETIC mutation in the immune system– dating back to a single common ancestor more than three centuries ago -- leads to chronic kidney disease, which seems to exclusively affect people of Cypriot origin,

What did I tell you? If your slovenly ancestors had remained "true Cypriots" and hadn't chosen the easy option to "convert" to Islam all those centuries ago during Ottoman rule, Cyprus wouldn't be in the mess she's in now. Granted, we'd still have kidney problems, but at least Turkey would be out of our hair.

Do you believe in FAITH healing

[Malapapa]

A GENETIC mutation in the immune system– dating back to a single common ancestor more than three centuries ago -- leads to chronic kidney disease, which seems to exclusively affect people of Cypriot origin,

What did I tell you? If your slovenly ancestors had remained "true Cypriots" and hadn't chosen the easy option to "convert" to Islam all those centuries ago during Ottoman rule, Cyprus wouldn't be in the mess she's in now. Granted, we'd still have kidney problems, but at least Turkey would be out of our hair.

Do you believe in FAITH healing

My folks weren't the ones to give up belief in their faith!

[zan]

A GENETIC mutation in the immune system– dating back to a single common ancestor more than three centuries ago -- leads to chronic kidney disease, which seems to exclusively affect people of Cypriot origin,

What did I tell you? If your slovenly ancestors had remained "true Cypriots" and hadn't chosen the easy option to "convert" to Islam all those centuries ago during Ottoman rule, Cyprus wouldn't be in the mess she's in now. Granted, we'd still have kidney problems, but at least Turkey would be out of our hair.

Do you believe in FAITH healing

My folks weren't the ones to give up belief in their faith!

Or maybe just changed it so many times that you have no idea where you came from....

[Malapapa]

A GENETIC mutation in the immune system– dating back to a single common ancestor more than three centuries ago -- leads to chronic kidney disease, which seems to exclusively affect people of Cypriot origin,

What did I tell you? If your slovenly ancestors had remained "true Cypriots" and hadn't chosen the easy option to "convert" to Islam all those centuries ago during Ottoman rule, Cyprus wouldn't be in the mess she's in now. Granted, we'd still have kidney problems, but at least Turkey would be out of our hair.

Do you believe in FAITH healing

My folks weren't the ones to give up belief in their faith!

Or maybe just changed it so many times that you have no idea where you came from....

I don't think so. Christianity was inspired by Stoicism, which was founded by a Cypriot (Zeno of Citium).

http://stoicism.biblestudyinfo.com/

And Cyprus – saint Paul's first stop – was the first Christian nation too, according to the New Testament! (The Roman proconsul converting in around AD 50).

Acts 13:6-13
http://www.biblegateway.com/passage/?se ... ersion=NIV

[zan]

A GENETIC mutation in the immune system– dating back to a single common ancestor more than three centuries ago -- leads to chronic kidney disease, which seems to exclusively affect people of Cypriot origin,

What did I tell you? If your slovenly ancestors had remained "true Cypriots" and hadn't chosen the easy option to "convert" to Islam all those centuries ago during Ottoman rule, Cyprus wouldn't be in the mess she's in now. Granted, we'd still have kidney problems, but at least Turkey would be out of our hair.

Do you believe in FAITH healing

My folks weren't the ones to give up belief in their faith!

Or maybe just changed it so many times that you have no idea where you came from....

I don't think so. Christianity was inspired by Stoicism, which was founded by a Cypriot (Zeno of Citium).

http://stoicism.biblestudyinfo.com/

And Cyprus – saint Paul's first stop – was the first Christian nation too, according to the New Testament! (The Roman proconsul converting in around AD 50).

Acts 13:6-13
http://www.biblegateway.com/passage/?se ... ersion=NIV

Converted from what and then how many peoples came and went

[Malapapa]

Dunno from what (Roman gods I would imagine); and it doesn't matter how many people came and went - true Cypriots have remained true to the faith inspired by Zeno of Citium.